Bis(2-hydroxyethyl) sulphone

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

The study was conducted between 09 April 2006 and 21 April 2006

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: vapour pressure balance

Specific details on test material used for the study:

Sponsor's identification: BHES-100X
Description: white solid block
Batch number: 5K0718-CC
Date received: 21 January 2006
Storage conditions: room temperature, over silica gel, in the dark

Key result

Test no.:

#5

Temp.:

25 °C

Vapour pressure:

< 0.001 Pa

No statistical analyses were performed because the balance readings were too low and variable for a line of best fit to have any meaning. Instead it was considered more appropriate to impose a regression slope on a chosen data point to provide an estimate of the maximum value for the vapour pressure at 25°C.

Run 5 was chosen because the sample had been under vacuum for the longest period prior to this run and so degassing would have been the most complete. The reading at 12°C (285.15 K) was chosen because this is the data point which gives the highest estimated vapour pressure at any given temperature when a slope of -1500 K is imposed upon it.

The value of -1500 K is an in-house value and is the shallowest slope observed whilst determining the vapour pressure on a wide range of samples using the vapour pressure balance method. Extrapolation to 25°C gave a vapour pressure of 7.769 x 10^-4 Pa which has been taken as a maximum for this material.

The test material did not change in appearance under the conditions used in the determination.

Conclusions:

The vapour pressure of the test material has been determined to be less than 7.8 x 10^-4 Pa at 25 °C.

Executive summary:

The vapour pressure was determined using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25 °C. Testing was conducted using Method A4 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67 /548/EEC). The vapour pressure of the test material has been determined to be less than 7.8 x 10^-4 Pa at 25 °C.

Description of key information

The vapour pressure was determined using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25 °C. Testing was conducted using Method A4 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67 /548/EEC). The vapour pressure of the test material has been determined to be less than 7.8 x 10^-4 Pa at 25 °C.

Key value for chemical safety assessment

Vapour pressure:

0.001 Pa

at the temperature of:

20 °C