Registration Dossier

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: short-term
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
Deviations:
no
Remarks:
Conducted according to guideline in effect at time of study conduct.
Qualifier:
according to
Guideline:
EU Method C.8 (Toxicity for Earthworms: Artificial Soil Test)
Deviations:
no
Remarks:
Conducted according to guideline in effect at time of study conduct.
Qualifier:
according to
Guideline:
EPA OPPTS 850.6200 (Earthworm Subchronic Toxicity Test)
Deviations:
no
Remarks:
Conducted according to guideline in effect at time of study conduct.
Qualifier:
according to
Guideline:
other: SEPA. The guidelines for the testing of chemicals. HJ/T 153-2004
Deviations:
no
Remarks:
Conducted according to guideline in effect at time of study conduct.
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Purity: 28 wt%

Sampling and analysis

Analytical monitoring:
no

Test substrate

Vehicle:
yes

Test organisms

Test organisms (species):
Eisenia fetida
Animal group:
annelids

Study design

Study type:
laboratory study
Substrate type:
artificial soil
Limit test:
yes
Total exposure duration:
14 d

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
> 1 000 mg/kg soil dw
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
other: no mortality
Remarks on result:
other: highest concentration tested

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
14-day LC50 (earthworms) > 1000 mg/kg dry weight soil.
Executive summary:

The acute toxicity of the test substance to earthworms, Eisenia fetida, was estimated in a 14-day soil exposure laboratory study conducted under OECD Guideline 207 in artificial soil. Based on the results of a range-finding test, a limit test was conducted. The 14-day LC50 and NOEC were determined to be greater than 1000 mg/kg dry weight soil.