2H-Tetrazol-5-amine, potassium salt (1:1)

Particle size distribution (Granulometry)

Administrative data

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: OECD-Guideline for the Testing of Chemicals Part 110 „Particle Size Distribution/Fibre Length and Diameter Distributions“

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

sedimentation (gravitational settling)

Test material

Test material information

Constituent 1

Reference substance name:

potassium 5-amino-1H-1,2,3,4-tetrazol-1-ide

Cas Number:

136369-04-5

Molecular formula:

CH2KN5

IUPAC Name:

potassium 5-amino-1H-1,2,3,4-tetrazol-1-ide

Test material form:

solid: particulate/powder

Details on test material:

Batch no.: 08KI030

Results and discussion

Particle size

Particle size 1

Key result

Percentile:

D90

Mean:

> 126.58 µm

Remarks on result:

other: No standard deviation stated in study report.

Particle size 2

Key result

Percentile:

D10

Mean:

< 126.58 µm

Remarks on result:

other: No standard deviation stated in study report.

Particle size 3

Key result

Percentile:

other: D100

Mean:

> 10 µm

Remarks on result:

other: No standard deviation stated in study report.

Applicant's summary and conclusion

Conclusions:

When comparing the two main studies, all measured values show good reproducibility, giving deviations of less than 5% for each fraction. The results of the experiments using the fixed pipette method showed good correlation to the screening test using sieve analysis: approximately 95% of the particles are larger than 100 μm. No particles smaller than 10 μm were detected, therefore, it can be assumed that the inhalative toxicity doesn’t have to be tested. The result of the test can be considered valid.

Executive summary:

The particle distribution of 5-Aminotetrazol Potassium was determined by sedimentation following ISO 13317-2 – Fixed Pipette. Method The determination was performed in duplicate, using kerosene (lamp oil) as suspending medium. Virtually no particles smaller than 10 μm were determined, therefore the inhalative toxicity doesn`t have to be tested.

For the test item, 5-Aminotetrazol Potassium, the following particle distribution was found:

Stokes-diameter in μm	Mass under particle size Exp. 1	Mass under particle size Exp. 2	Mass under particle size Mean
126.58	8.27 %	9.60 %	8.94 %
71.58	3.01 %	1.60 %	2.30 %
54.74	3.76 %	3.20 %	3.48 %
45.46	0.00 %	1.60 %	0.80 %

Most of the particles are larger than 126 μm (upper Stokes diameter) and their distribution could not be measured using the Fixed Pipette Method.