Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 433-180-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1999-04-20 to –1999-04-22
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study according to GLP and guideline
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Details on test material:
- -Name of test material (as cited in study report): Reaktiv-Orange DYPR934
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Concentration: 100 mg/L
- Sampling method: According to the study method; i.e. SOP 2030-7000203-98 D
- Sample storage conditions before analysis: As recommended in the guideline
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
Species: Daphnia magna STRAUS, parthenogenetic females
Origin of species: cloned at the Federal Health office (BGA) in Berlin
Test animals: Laboratory bred at Bayer AG Leverkusen
Age of test animals: 0-24 h
Keeping conditions: SOP 2030-7700203-98 D
Keeping water: M4-Medium according to Elendt and BGA (1992)
SEPARATION OF THE TEST ANIMAL ACCORDING TO SIZE BEFORE START OF TEST
1st sieving on: 1999.04.19 at 2.00 p.m.
2nd sieving on: 1999-04-20 at 8.00 a.m.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Remarks on exposure duration:
- Test parameters during the test: -Oxygen [mg/L]-pH-Water temperature [°C] number of immobile daphnids after 24 h (compare SOP 2030-7000203-96 D) and 48 h
- Post exposure observation period:
- Analysis of the only test concentration plus a control test at test start and after 48 h of exposure.
Test conditions
- Hardness:
- 15.4 mg CaCO3/L
- Test temperature:
- 19.9 to 20
- pH:
- 7.9
- Dissolved oxygen:
- 8.6 mg/L
- Salinity:
- freshwater
- Nominal and measured concentrations:
- Nominal concentration: 100 mg/L
- Details on test conditions:
- No Deviations from the SOPs
STUDY CONDITIONS (SOP 2030-7000203-98 D)
OPERATING CONDITIONS: Static system in accordance with above study method.
Photoperiod: 16hours light / 8hours dark
TEST PROCEDURE:
-cylindrical test vessels
-diameter 4.0 cm, height 6.5 cm
-20 mL test medium
-not ventilated
Method of administration: direct weighing (SOP 2030-6600401-96 D)
Test concentration/s (mg/L): 100
Solubilizer or other auxiliaries: none
Control/Water for dilution: M4-Medium according to Elendt and BGA (1992)
Test parameters during the test: oxygen [mg/L], pH, water temperature (°C), number of immobile daphnids after 24hours (compare SOP 2030-7000203-98 D) and 48 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- >= 100 mg/L
- Nominal / measured:
- nominal
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- >= 99.1
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- other: (Test substance; including inorganic components)
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- > 67.4 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- other: (organic components)
- Details on results:
- Mortality=0
- Mortality of control=0
-Other adverse effects control:0
EC10 > 100 mg/l (48 h, Daphnia magna)
Any other information on results incl. tables
NOEC:
67.4 mg/L mg/l
Maximum
test concentration causing no mortality: 100 mg/L(nominal).
Minimum
test concentration causing 100% mortality: NA
STUDY EVALUATION –TEST SUBSTANCE (SOP 2030-7001202-96 D, 2030-1110101-96 D, 2030-7000203-98D) No. parallel solutions : 2 Test volume : 20 mL No. daphnids per vessel: 10 |
|||||||
Nominal Concentration test substance [mg/L] |
Results after 24 hours and 48 hours |
||||||
Imobile daphnids absolute % |
Oxygen [mg/L] 48 h |
pH 48 h |
Temperature [°C] 48 h |
||||
Control |
0 |
0 |
0 |
0 |
8.6 |
7.9 |
20.0 |
100 |
0 |
0 |
0 |
0 |
8.6 |
7.9 |
19.9 |
Remark: the value of the abiotic parameters (oxygen, pH and temperature) were determined from the total of the parallel solutions.
Study results
after 24 hours
|
After 48 hours |
Nominal concentration
|
Arithmetic mean of analytical values
|
EC0: >= 100 mg/L |
>= 67.4 mg/L (organic components) >= 99.1 mg/L (test substance; including inorganic components) |
The above test result refers to a concentration of the test substance, which was calculated directly from analytically determined TOC values. According to the relevant product informations, 1 mg/L TOC equals to 2.75 mg/L of the organic components of the test substance mw: 685 g/mol and 766 g/mol). As these organic components correspond to 68% of the molecular weight of the test substance, 100 mg/L of the test substance equal to 25 mg/L of organic C. Thus the above analytical values indicate a very good recovery rate.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- The values of the abiotic parameters (oxygen, pH and temperature) were determined from the total volume of the parallel solutions. The validity criteria were fulfilled.
- Conclusions:
- The above analytical value indicates a very good recovery rate. Therefore the results are considered as valid.
- Executive summary:
The acute Daphnia toxicity of Reaktiv-Orange DYPR 934 was tested in a static system within 24 and 48 h respectively according to SOP 2030 -7000203 -98 D which is similar to the EU C2 (acute toxicity to daphnia).
The values of the abiotic parameters (oxygen, pH and temperature) were determined from the total volume of the parallel solutions.
The validity criteria were fulfilled. The analytical value indicates a very good recovery therefore the following results are considered as valid:
Study results
after 24 hours
After 48 hours
Nominal concentration
Arithmetic mean of analytical values
EC0: >= 100 mg/L
>= 67.4 mg/L (organic components)
>= 99.1 mg/L (test substance; including inorganic components)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Aunque la ECHA ofrece una gran cantidad de material en su idioma, una parte de esta página está solo disponible en inglés. Más información sobre la política de multilingüismo de la ECHA.
Bienvenido a la página web de la ECHA. Este sitio no es plenamente compatible con Explorer 7 (y versiones anteriores). Por favor, actualice su Internet Explorer a una versión más reciente.
Esta web utiliza cookies para mejorar su experiencia de navegación en nuestros sitios web.
Más información sobre el uso de cookies.