Registration Dossier
Registration Dossier
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EC number: 283-952-1 | CAS number: 84776-27-2 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Cinchona officinalis, Rubiaceae.
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
Description of key information
From the calculations it can be expected, that the read across substance quinine is not readily biodegradable. Thus totaquina which constist of 75 % quinine is also not readily biodegradable
Key value for chemical safety assessment
- at the temperature of:
- 25 °C
- at the temperature of:
- 25 °C
Additional information
The given biodegradability is calculated from BIOWIN 4.10 using the models BioWin3 and BioWin5. From these models it is shown, that the read across substance quinine is not readily biodegradable. Thus totaquina, which constist of 75 % quinine, is also not readily biodegradable. Nevertheless, the EPA recommends that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available. However, empirical studies have not been done, so that we have to consider, that the substance is not readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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