Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 203-870-1 | CAS number: 111-44-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Description of first aid measures
General advice: Call a physician immediately. First aider needs to protect himself.
If inhaled: IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. If breathing is irregular or stopped, administer artifical respiration. Call a physician immediately.
In case of skin contact: Wash off with polyethylene glycol and afterwards with plenty of water. Take off contaminated clothing and shoes immediately. Call a physician immediately.
In case of eye contact: In case of eye contact, remove contact lens and rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Call a physician immmediately.
If swallowed: Clean mouth with water and drink afterwards plenty of water. Induce vomiting if person is conscious. Call a physician immediately.
Notes to physician
Hazards: Inhaled corrosive substances can lead to a toxic oedema of the lungs. Liver and kidney injuries may occur.
Symptoms. Shortness of breath, Diarrhoea, Cough, Irritation of mucous membranes.
Treatment: Treat symptomatically.
Fire-fighting measures
Extinguishing media
Suitable extinguishing media: Carbon dioxide (CO2), Dry powder, Sand, Foam, Water spray
Extinguishing media which must not be used for safety reasons: Do not use a solid water stream as it may sctter and spread fire.
Special hazards arising from the substance or mixture
Special exposure hazards arising from the substance or preparation itself, its combustion products, or released gases: Gaseous hydrogen chloride (HCl). Carbon oxides. Phosgene. In use, may form flammable/explosive vapour - air mixture.
Advice for firefighters
Special protective equipment for firefighting: Personal protection through wearing a tightly closed chemical protection suit and a self-contained breathing apparatus.
Additional information on fire-fighting: Remove all sources of ignition. Pay attention to flashback. Vapours are heavier than air and may spread along floors.
Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal precautions: Keep people away from and upwind of spill/leak. Use personal protective equipment. Avoid contact with skin, eyes and clothing.
Environmental precautions
Environmental precautions: Prevent spreading over a wide area (e.g. by containment or oil barriers). Suppress (knock down) gases/vapours/mists with a water spray jet. Do not flush into surface water or sanitary sewer system. Do not let product enter drains. Vapours are heavier than air and may spread along floors. Risk of explosion.
Methods and material for containment and cleaning up
Methods for cleaning up: Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section Disposal considerations). After cleaning, flush away traces with water.
Handling and storage
This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17 (3) for on-site isolated intermediates and, in case the substanxce is transported to other sites for further processing, the substance should be handled at these sites under the strictly controlled conditions as specified in REACH regulation Article 18 (4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each Manufacturing site.
Written confirmation of application of Strictly Controlled Conditions has been received from affected Distributor and Downstream Manufacturer/User of the Registrant's intermediate.
Precautions for safe handling
Advice on safe handling: Refill and handle product only in closed system. Avoid breathingvapors, mist or gas. Avoid formation of aerosol.
Advice on protection against fire and explosion: Keep away from heat and sources of ignition. Take precautionary measures against static discharges. Vapours may form explosive mixture with air.
Conditions for safe storage, including any incompatibilities
Storage space and container requirements: keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from heat. Keep away from open flames, hot surfaces and sources of ignition.
VCI storage category: 3A
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 1916
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Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- -
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Marine transport (UN RTDG/IMDG)
- UN number:
- 1916
Shipping information
- Proper shipping name and description:
- 2,2'-DICHLORODIETHYL ETHER
- Chemical name:
- bis(2-chloroethyl) ether
- Labels:
- 6.1, 3
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 1916
Shipping information
- Proper shipping name and description:
- 2,2'-Dichlorodiethyl ether
- Chemical name:
- bis(2-chloroethyl) ether
- Labels:
- 6.1 - Toxic Substance; 3 - Flammable liquid
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Exposure controls / personal protection
This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17 (3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18 (4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each Manufacturing site.
Written confirmation of application of Strictly Controlled Condistions has been received from affected Distributor and Downstream Manufacturer/User of the Registrant's Intermediate.
Control parameters
Exposure controls
Respiratory protection: Breathing apparatus with filter. Recommended Filter type: ABEK.
Hand protection:
Suitable material: butyl-rubber
Material thickness: 0.7 mm
Break through time. > 480 min
Suitable material: Nitrile rubber
Material thickness: 0.4 mm
Break through time: > 60 min
Eye protection: Tightly fitting safety goggles
Skin and body protection: Long sleeved clothing. Wear as appropriate. Complete suit protecting against chemicals.
General protective and hygiene measures: Smoking, eating and drinking should be prohibited in the application area. Contaminated work clothing should not be allowed out of the workplace. Take off contaminated clothing and shoes immediately. Avoid breathing vapours, mist or gas. Wash hands and face before breaks and immediately after handling the product. Avoid contact with skin, eyes and clothing. Keep away from food, drink and animal feedingstuffs. Use protective skin cream before handling the product.
Stability and reactivity
Possibility of hazardous reactions
Hazardous reactions: Vapours may form explosive mixtures with air. May form explosive peroxides.
Conditions to avoid
Conditions to avoid: Vapour/air-mixtures are explosive at intense warming. Heat, flames and sparks.
Incompatible materials
Materials to avoid: Acids, Oxidizing agents, NaOH, KOH, LiOH, NaNH2
Hazardous decomposition products: Hydrogen chloride gas, Carbon monoxide, Carbon dioxide (CO2)
Disposal considerations
Waste treatment methods
Disposal considerations: Must be incinerated in a suitable incineration plant holding a permit delivered by the competent authorities.
Uncleaned empty packaging: Dispose of as unused product.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.