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EC number: 209-798-7 | CAS number: 593-56-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restrictions.
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
- Reference Type:
- other: recalculation with ToxRatPro Version 2.09 (2005)
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
- Reference Type:
- secondary source
- Title:
- European Union Risk Assessment Report BIS(HYDROXYLAMMONIUM)SULPHATE CAS No: 10039-54-0 EINECS No: 233-118-8,
- Author:
- ECB
- Year:
- 2 008
- Bibliographic source:
- Final approved version, May 2008
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38412 Part 9
- GLP compliance:
- no
Test material
- Reference substance name:
- Bis(hydroxylammonium) sulphate
- EC Number:
- 233-118-8
- EC Name:
- Bis(hydroxylammonium) sulphate
- Cas Number:
- 10039-54-0
- Molecular formula:
- H3NO.1/2H2O4S
- IUPAC Name:
- bis(hydroxyammonium) sulfate
- Details on test material:
- - Analytical purity: > 99%
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: The stock solution (1g/l) was diluted to 10 mg/l. From this stock solution target concentrations were prepared with dilution with test water.
- Evidence of undissolved material (e.g. precipitate, surface film, etc): no
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
- Details on test organisms:
- TEST ORGANISM
- Common name: Desmodesmus subspicatus (former name: Scenedesmus subspicatus)
- Strain: CHODAT SAG 86.81
- Source (laboratory, culture collection): Supplier: Sammlung für Algenkulturen der Universität Göttingen
- Age of inoculum (at test initiation): The test algae are taken from a 3 days-old continously growing preculture
- Method of cultivation: The test strain is kept in liquid culture in the laboratory.
ACCLIMATION
- Acclimation period: 3 days
- Culturing media and conditions (same as test or not): same as test medium
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 20°C
- pH:
- 8.1-10
- Nominal and measured concentrations:
- 0, 0.039, 0.078, 0.156, 0.312, 0.625, 1.25, 2.5 and 5 mg/l nominal
- Details on test conditions:
- TEST SYSTEM
- Type (delete if not applicable): closed
- Material, size, headspace, fill volume: 20 ml glass tubes with flat bottom, plugged with siliconesponge caps, 10 ml test volume
- Aeration: no
- Initial cells density: 10000 cells/ml
- Control end cells density: yes
- No. of vessels per concentration (replicates): 5
- No. of vessels per control (replicates): 5
GROWTH MEDIUM
- Standard medium used: yes
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: according to OECD 201
OTHER TEST CONDITIONS
- Adjustment of pH: not during test
- Photoperiod: continous
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
- Determination of cell concentrations: in vivo chlorophyll-a-fluorescence at 685 nm wavelength after 0, 24, 48, 72 and 96 hours
- pH values: after 0 and 96 hours
TEST CONCENTRATIONS
0.039, 0.078, 0.156, 0.312, 0.625, 1.25, 2.5 and 5 mg/l (nominal). A control was tested in parallel. - Reference substance (positive control):
- yes
- Remarks:
- Potassium chromate p.a.
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.156 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: Re-calculation of critical concentrations of BASF AG Algae test 289/89 (BASF AG 2007, 02/w289/88)
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1.043 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: Re-calculation of critical concentrations of BASF AG Algae test 289/89 (BASF AG 2007, 02/w289/88)
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- 0.529 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: Re-calculation of critical concentrations of BASF AG Algae test 289/89 (BASF AG 2007, 02/w289/88)
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.674 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- yield
- Remarks on result:
- other: Re-calculation of critical concentrations of BASF AG Algae test 289/89 (BASF AG 2007, 02/w289/88)
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- 0.353 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- yield
- Remarks on result:
- other: Re-calculation of critical concentrations of BASF AG Algae test 289/89 (BASF AG 2007, 02/w289/88)
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.72 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: yield
- Remarks on result:
- other: result of BASF AG 1988
- Duration:
- 72 h
- Dose descriptor:
- EC20
- Effect conc.:
- 0.42 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: yield
- Remarks on result:
- other: result of BASF AG 1988
Any other information on results incl. tables
Summary of results (BASF AG 1988):
96h: EC20 = 0.52; EC50 = 0.86; EC90 = 1.64 mg/l
72h: EC20 = 0.42; EC50 = 0.72; EC90 = 1.24 mg/l
48h: EC20 = 0.38; EC50 = 0.61; EC90 = 3.04 mg/l
24h: EC20 = 0.43; EC50 = 0.92; EC90 = ---- mg/l
No chemical dose verification was performed. All values refer to nominal test concentrations of Bis(hydroxylammonium) sulphate.
-------------------------------------------------------------------------------------------------------
In a new mathematical evaluation, critical concentrations of BASF AG Algae test 289/89, has been re-calculated, in order to allow an assessment based on growth rate and biomass (according to the requirements given in OECD guideline 201). (BASF AG 2007, 02/w289/88)
The mathematical evaluation was based on a linear relationship between fluorescence and cell number and raw data were equated with cell numbers.
Summary of Results for all Endpoints: Critical effect and threshold concentration as observed at end of experimental time; EC: Effective concentration for xx% reduction; LOEC: Lowest observed effect concentration; NOEC: No observed effect concentration
a) Yield
Critical conc (mg/L)/ 0 -24h/0 -48h /0 -72h/0-96h
EC10/ 0.182/ 0.292/ 0.353/ 0.460
EC20/ 0.357/ 0.378 / 0.441/ 0.554
EC50/ 1.279/ 0.619/ 0.674/ 0.792
LOEC/ 0.312/ 0.312/ <0.039/ 0.625
NOEC/ 0.156/ 0.156/ <0.039/ 0.312
b) Growth rate
EC10/ 0.311/ 0.424/ 0.529/ 0.758
EC20/ 0.412/ 0.526/ 0.668/ 0.917
EC50/ 0.701/ 0.794/ 1.043/ 1.318
LOEC/ 0.312/ 0.625/ 0.312/ 0.625
NOEC/0.156/ 0.312/ 0.156/ 0.312
c) Sectional growth rate
EC10/ 0.311/ 0.538/ 0.974/ 1.531
EC20/ 0.412/ 0.633/ 1.153/ 1.609
EC50/ 0.701/ 0.865/ 1.589/ 1.768
LOEC/ 0.312/ 0.625/ 2.500/ 2.500
NOEC/ 0.156/ 0.312/ 1.250/ 1.250
d) Biomass integral
EC10/ 0.284/ 0.300/ 0.330/ 0.393
EC20/ 0.365/ 0.376/ 0.411/ 0.481
EC50/ 0.586/ 0.576/ 0.624/ 0.706
LOEC/ 0.312/ 0.312/ 0.312/ 0.312
NOEC/ 0.156/ 0.156/ 0.156/ 0.156
* for 95% Confidence limits, please see BASF AG (2007), 02/w289/88
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.