Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-308-5 | CAS number: 105-55-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
Description of key information
According to 3 studies including SEM, dry granulometry (Malvern) and SIEVING, the mean diameter of DETU (1,3-diethyl-2-thiourea) is between 500 et 1000 um. About 8% of particles are higher to 1000 um = 1mm, and only some percents (ca 4%) are lower to 63%.
DETU is not considerer as dusty (low dustisseness)
Additional information
Three methods are used for granulometry calculation:
1/ SEM:Using scanning microscopy observation, DETU form of particles can be observed. Two types of forms are shown:
-particles of rather large oval sizes with diameters between 200 microns and 2 mm,
-and particles with multiple fractures with dimensions that can be reduced up to 20um, the great length generally exceeding 50-100 microns.
It would appear that the DETU be particularly prone to fracture (brittle molecule) and having a particle distribution between 20 and 2000 microns, the particles are rather large.
2/ Dry laser measurement (Malvern):A study was performed at GRL (Arkema) to investigate the particle size distribution (granulometry) on one batch of the test substance EKALAND DETU CR (1,3 -diethyl-2 -thiourea). The study was conducted according to ISO 13320- 1 “International standard for Laser Diffraction Measurements – Principles of Laser diffraction” and in accordance with OECD Test Guideline 110. The mean particle size, number in volume, of DETU PD test item, is determined to be about 375µm, with 10% of particles presenting a diameter less than 125µm, and 10% of particles presenting a diameter larger than 700µm.
3/ Sieving:According to a granulometry study (sieving) OECD 110 made at MLPC International, the mean diameter of DETU is between 500 and 1000 um. 6% of the particles are higher to 1000 um = 1mm and only 4% are lower to 63um.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.