Registration Dossier
Registration Dossier
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EC number: 210-557-3 | CAS number: 618-62-2
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- secondary source
- Title:
- IUCLID DATAFILE
- Author:
- unknown
- Year:
- 2 000
- Bibliographic source:
- Esis-Database, European Chemicals Bureau
Materials and methods
Test guideline
- Guideline:
- EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion)
- GLP compliance:
- no
Test material
- Reference substance name:
- 3,5-dichloronitrobenzene
- EC Number:
- 210-557-3
- EC Name:
- 3,5-dichloronitrobenzene
- Cas Number:
- 618-62-2
- Molecular formula:
- C6H3Cl2NO2
- IUPAC Name:
- 1,3-dichloro-5-nitrobenzene
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Vehicle:
- unchanged (no vehicle)
- Observation period (in vivo):
- 7 d
- Number of animals or in vitro replicates:
- 4
Results and discussion
Any other information on results incl. tables
Based on the interpretation of the results, the substance can be classified as slightly irritating to eye.
Applicant's summary and conclusion
- Interpretation of results:
- moderately irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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