Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The information concerning the aquatic toxicity of Thioglycolic acid (TGA) are summarized hereafter:

Acute toxicity to fish: LC50_96h > 100 mg/L

Acute toxicity to daphnia: EC50_48h = 35.8 mg/L

Long-term toxicity to daphnia: NOEC = 2.7 mg/L

Toxicity to algae: ErC50_72h = 35.65 mg/L and ErC10_72h = 0.8 mg/L.

Additional information

Based on the overall information available for thioglycolic acid, its salts but also oxidation product, the substances can be considered as harmful for aquatic species (invertebartes and algae).

Diammonium dithiodiglycolate occurs rapidly in the environment based on practical case (Devaux, 2003) when thioglycolic acid is released. Diammonium dithiodiglycolate data also exists for Daphnia and demonstrates that this form is neither toxic nor harmful. One could consider that thioglycolic acid is also of no concern for Daphnia based on its half-life in water. Nevertheless as valid data exists on the thioglycolic acid, the applicant prefers to retain this result and concludes that thioglycolic acid is harmful to Daphnia.