Registration Dossier
Registration Dossier
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EC number: 500-047-1 | CAS number: 26316-40-5 1 - 4.8 moles ethoxylated and 1 - 8.5 moles propoxylated
Endpoint summary
Administrative data
Description of key information
Additional information
Biodegradation in water was tested in two screening studies, according to OECD guideline 301F ("ready biodegradability") and 302B (inherent biodegradability). EDA EO PO showed limited mineralisation in the stringent 301F test, but in the 302B test an average 48.5% (and up to 61%) biodegradation by DOC removal was observed. It was formally concluded from this test that the EDA EO PO exhibits inherent (primary) biodegradability, not fulfilling specific criteria. This study, along with evidence from QSAR analyses, indicate the potential for ultimate biodegradability of the UVCB substance and its expected degradation products.
Additional simulation tests are waived, on the basis that the chemical safety assessment is already indicating sufficient margin of safety in the PEC/PNEC ratios for surface waters, sediments, and soil. Furthermore, exposure to the soil compartment can be regarded as improbable. However, ECHA has requested to demonstrate the removal efficiency in STP. Then a simulation test using activated sludge from waste water treatment plant was conducted and showed that biodegradation rate of EO PO EDA polyol was between 70 and 80 percent with a 95% confidence interval between 25 and 100 percent. As a worst-case, 25% degradation was incorporated into the manufacturing scenario.
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