Registration Dossier

Administrative data

Link to relevant study record(s)

Description of key information

No toxicokinetic (absorption, metabolism, distribution, elimination) data is available for MEA-Polyborate. Available data is primarily physico-chemical properties that influence the absorption and distribution of the substance in the body. Both 1:1 and 1:3 mole ratios of MEA to boric acid are infinitely soluble in water with log Pow of -0.9 for the polyborate moiety by ICP-MS and log Pow of -2.5 for the organic moiety by LC-MS. The log P values indicate that both ratios of MEA-Polyborate will likely be 100% absorbed in the gastrointestinal track, primarily found in the blood serum and excreted primarily via the kidneys in the urine. The log P values also indicate that both ratios of MEA-Polyborate is poorly absorbed through the skin with dermal absorption rates similar to monoethanolamine. No data is available on the metabolism of MEA-Polyborate.

Key value for chemical safety assessment

Additional information