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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

8-day NOEL = 3.2 mg/L loading rate WAF (nominal), OECD 211, EPA OPPTS 850.1300, Priestly & Mullee (2010)

Key value for chemical safety assessment

Additional information

The effect of the test material on the survival and reproduction of Ceriodaphnia dubia over an 8-day period was investigated in a study which was conducted under GLP conditions and in accordance with the standardised guidelines OECD 211 and EPA OPPTS 850.1300.

During the study, Ceriodaphnia dubai were exposed to Water Accommodated Fractions of the test material over a range of nominal loading rates of 1.0, 3.2, 10, 32 and 100 mg/L for a period of 8 days. The WAFs were renewed 3 times. The numbers of live and dead adult Ceriodaphnia and young daphnids (live and dead) were determined daily.

Under the conditions of the study, the 8-day EL*50 (immobilisation) value, based on nominal loading rates, for the parental Ceriodaphnia dubia generation (P1) was calculated to be 27 mg/L loading rate WAF with 95% confidence limits of 32-100 mg/L loading rate WAF. The 8-day EL*50(reproduction) based on nominal loading rates was 11 mg/L loading rate WAF with 95% confidence limits of 6.5 -20 mg/L loading rate WAF. The ''Lowest Observed Effect loading rate'' (LOEL) and the ''No Observed Effect Loading rate'' (NOEL) based on nominal loading rates were 10 and 3.2 mg/L loading rate WAF, respectively.