Registration Dossier
Registration Dossier
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EC number: 204-984-4 | CAS number: 130-26-7
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
Description of key information
Half life period of clioquinol in water is observed to be 38 days (912 hrs.) while in sediment it is 340 days (8160 hrs).Based on these half life values ofclioquinol, it is concluded that the chemical is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is slight diffusion of the substance in the sediment as evident from the reported data (3% in sediment) and hence persistence in the sediment compartment is not likely to be critical.
Key value for chemical safety assessment
- Half-life in freshwater:
- 38 d
- at the temperature of:
- 25 °C
- Half-life in freshwater sediment:
- 340 d
- at the temperature of:
- 25 °C
Additional information
Based on the Level III Fugacity Model, the half life period of theclioquinolwas estimated. The half period ofclioquinolin water is 38 days (912 hrs) therefore it is considered that the substance will qualify as not persistent as the half life does not exceed the threshold of 60 days. So, it can be confirmed that the substance is readily biodegradable in water medium where as in sediment the half life is 340 days (8160 hrs).
Based on this value, it can be inferred that the substance is persistent in sediment medium and is not readily biodegradable probably due to the anaerobic conditions existing in most sediments. However, it can be observed that clioquinol have very slightdiffusion in the sediment medium since it's percentage in the sediment medium is reported to be 3% and hence persistence in the sediment compartment is not likely to be critical.
Media |
Half-Life |
Percent in |
Water |
38 |
11% |
Sediment |
340 |
3 % |
Media |
Half life (hrs) |
Percent in Medium |
Emission (kg/hr)
|
Water |
900 |
10.8 |
1000 |
Sediment |
8100 |
3.38 |
0 |
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