Formaldehyde, oligomeric reaction products with aniline

Additional toxicological data

Administrative data

Endpoint:

additional toxicological information

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Acceptable study report which meets basic scientific principles

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2000

Report date:

2000

Materials and methods

Type of study / information:

Glove resistance to permeation

Principles of method if other than guideline:

Glove tests was performed according to EN 374-3, part 3 (Determination of resistance to permeation by chemicals ), with polymeric MDA (pMDA) as test chemical.

Test material

Test material information

Constituent 1

Reference substance name:

Formaldehyde, oligomeric reaction products with aniline

EC Number:

500-036-1

EC Name:

Formaldehyde, oligomeric reaction products with aniline

Cas Number:

25214-70-4

Molecular formula:

(C6 H7 N)2 (C H2)x+1(C6H6N)x or C7x+13H6x+13Nx+2

IUPAC Name:

Poly[(aminophenyl)methyl]aniline

Details on test material:

- Name of test material (as cited in study report) :polymeric MDA (pMDA)

Results and discussion

Any other information on results incl. tables

Test No.	Glove type	Material	Color	Thickness (mm)	Permeation (min)	Protection index (EN 374)
1	Uvex Profas Profi NB 20A	nitrile rubber	Orange red	0.65-0.732	> 480	6 a
2	Uvex Profas Profi NB 40 S	nitrile rubber	White green	1.13-1.15	> 480	6
3	MAPA Baltex Latex 740604	natural rubber	Orange red	1.101-1.114	> 480	6
4	Sempermed	natural rubber	Transparent	0.104-0.109	< 10	Failed
5	MAPA Professionel Technic 450	chloroprene rubber	black	0.728 -0.733	> 480	6
6	NSP	PVC	Rusty brown	0.509-0.511	> 120	4
7	Comasec Normal 35	PVC	Rusty brown	1.220-1.245	> 480	6
8	MAPA Jerselite 307316	natural rubber	Violet	0.700-0.708	> 60	3
9	VENITEX Toutravo Ref. 509	neopren rubber	Black	0.801-0.809	> 480	6 b
10	Sensiflex	flexible soft foil	transparent	0.07	< 10	Failed

a: only partially coated

b: these gloves contain traces of free aniline

 

 

Two types of gloves (nos. 4 and 10) were made from thin latex. They failed the test for all protection index classes. Both gloves showed no resistance to pMDA at the lowest class conditions (< 10 minutes). On the one hand, gloves of this type were used for laboratory work only, but on the other hand laboratory work normally involves solvent use too. In any case, potential encouragement of the permeation of pMDA if wetted by solvent contact cannot be excluded when laboratory work is performed. Two black gloves (nos. 5 and 9) seemed to be identical on first impression. They both gave a positive result on aniline after the 8-hour test. However, that the materials were

pre-contaminated with traces of aniline. The resistance against pMDA was cass 6 for no. 9, Venitex Toutravo. In contrast to this, no. 5, MAPA Professionnel Technic, was significantly worse (class 2). About 0.l µg/cm2 aniline in 100 cm2 extracted material was found for each glove.

The following gloves are stable against permeation by pMDA for at least 8 hours at a temperature range of 23 to 27 °C:

- Uvex Profas Rubiflex NB 40 S, nitrile rubber,

- MAPA Baltex Latex 740604, natural rubber,

- MAPA Professionel Tecnic 450, and

- Comasec Normal 35, PVC