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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

A full discussion on the justification on read-across of data for the 4,4´-isomer of MDA for oligomeric MDA in the scope of REACH is presented in section 7.6 of this CSR.

In the TNO study toxic effects of 4,4'-MDA were observed. Valid results from this short term toxicity test with earthworms were obtained. Results from long-term tests are not available. Therefore the LC50 value of 444 mg MDA/Kg soil (d.w.) may be considered together with an assessment factor of 1000, to derive a PNEC value.