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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22 September 2015 - 13 October 2015
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
(2Z)-3-(3-chloro-2-fluorophenyl)-2-(4-chloro-2-fluorophenyl)prop-2-enenitrile
EC Number:
806-533-2
Cas Number:
1219086-87-9
Molecular formula:
C15 H7 Cl2 F2 N
IUPAC Name:
(2Z)-3-(3-chloro-2-fluorophenyl)-2-(4-chloro-2-fluorophenyl)prop-2-enenitrile
Test material form:
other: solid
Details on test material:
Lot no. FIS201405080058
Molecular formula C15H7Cl2F2N
Molecular mass 310.13 g/mol
Purity 101.2 % (m/m)
Test item storage at room temperature, protected from light and humidity
Stability Stable under storage conditions
Expiry date 11 June 2016

Results and discussion

Water solubility
Water solubility:
< 20 µg/L
Temp.:
20 °C
pH:
ca. 4 - <= 6

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The water solubility of PAC-Ethenenitrile is below the limit of quantification of 0.02 mg/L at 20 °C and a pH ranging from 4.4 to 6.0.
Executive summary:

The water solubility of PAC-Ethenenitrile (CAS no. 1219086-87-9) was determined according to TG OECD 105. Several test vessels containing ultra-pure water mixed with test item in great excess (initial amount of test item about 1 g per liter water), were incubated and stirred for different periods of time at 30 °C (saturation phase), and then transferred to 20 °C for 24 h (equilibration phase). A sample from each test vessel was subsequently filtered with glass fiber filter and the concentration of test item in the clear aqueous phase was determined with HPLC.

The measured concentrations were as follows:

<0.02 mg/l after 1 day at 30°C, followed by 24 h at 20°C, pH 6.0

<0.02 mg/l after 2 days at 30°C, followed by 24 h at 20°C, pH 5.1

<0.02 mg/l after 3 days at 30°C, followed by 24 h at 20°C, pH 4.4

<0.02 mg/l after 7 days at 30°C, followed by 24 h at 20°C, pH 4.6

Since the pH was still decreasing after 1, 2 and 3 days, the test was prolonged by using longer equilibration times, and the concentration was also determined after 7 days. The water solubility of PAC-Ethenenitrile is below the limit of quantification of 0.02 mg/L at 20 °C and a pH ranging from 4.4 to 6.0. The validity criterion as specified in TG OECD 105 could be evaluated, as the water solubility of the test item is below the limit of quantification of the applied HPLC method.