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Diss Factsheets
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EC number: 444-960-2 | CAS number: 39148-16-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil microorganisms
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
No effects in soil microorganisms are expected, thus further testing can be omitted.
Key value for chemical safety assessment
Additional information
In accordance with Regulation (EC) No 1907/2006, Column 2 of Annex IX, section 9.4, toxicity tests on terrestrial organisms do not need to be investigated if the outcome of the chemical safety assessment shows no indication of risk on terrestrial organisms from exposure to the substance in question. The vapour pressure of the substance is below the limit of detection, thus the compound is unlikely to evaporate and air cannot be considered as route of exposure for this substance. Due to the high water solubility of Fosetyl-sodium (770 g/L at 20 °C and pH 5) and the low log Kow (log Kow = - 2.5 at 20 °C and a pH of 2.5 – 2.6) water is the main exposure route for this substance. Because the compound is inherently biodegradable (86.9% biodegradation after 28 days based on BOD and > 99.9% biodegradation after 28 days based on residue analysis), it is not considered to be persistent in the aquatic environment. However, the log Koc for Fosetyl-Sodium ranges from 2.79 – 3.96 (Koc = 613.9 – 9216 L/kg), therefore, the substance shows potential for adsorption to the soil compartment. For the terrestrial compartment one short-term toxicity test with the earthworm Eisenia fetida is available, which resulted in a 14-day LC50 of > 1000 mg/kg soil dry weight. Furthermore, a short-term study on the toxicity of Fosetyl-Sodium on the seed germination and root elongation of 10 plant species is available. The results of the study showed that the test substance had no effects on seed germination and root elongation in any of the 10 plant species up to the highest tested concentration of 1000 mg/L (nominal). In the aquatic environment, the lowest chronic effect value was observed for Daphnia magna with a NOEC (21 d) of ≥ 10 mg/L (nominal). No acute aquatic effects were observed in any of the three trophic levels fish, daphnia, and algae (LC/EC50 > 100 mg/L, nominal). In conclusion, taking into account the physio-chemical parameters of the substance and the lack of acute terrestrial effects combined with the lack of acute and chronic aquatic effects, no effects on soil microorganisms are expected and further testing can be omitted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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