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Diss Factsheets
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EC number: 425-450-9 | CAS number: 294-90-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- GLP compliance:
- yes
- Inoculum or test system:
- other: Migrated from NONS file. Not available.
- Reference substance:
- acetic acid, sodium salt
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 8
- Sampling time:
- 28 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 5
- Sampling time:
- 1 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 4
- Sampling time:
- 4 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 6
- Sampling time:
- 7 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 5
- Sampling time:
- 14 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 8
- Sampling time:
- 21 d
- Details on results:
- Points of degradation plot (test substance):5 % degradation after 1 d4 % degradation after 4 d6 % degradation after 7 d5 % degradation after 14 d8 % degradation after 21 d8 % degradation after 28 d
- Results with reference substance:
- Points of degradation plot (reference substance):2 % degradation after 1 d93 % degradation after 4 d94 % degradation after 7 d95 % degradation after 14 d97 % degradation after 21 d98 % degradation after 28 d
- Interpretation of results:
- other: Not readily biodegradable
- Remarks:
- Migrated information criteria used for interepretation of results: EU
- Conclusions:
- For the 28 days study, substance presented an 8% degradation (doc removal) meaning that substance was not readily biodegradable.
- Executive summary:
The ready biodegradability of the test susbstance was performed according to OECD Guideline 301E by the "Modified OECD screening test".
In this test the degradation of test substance was measured the following days (1, 4, 7, 14, 21, 28 d) using as a reference substance sodium acetate. The reference substance at day 28 showed a 98% degradation.
In the conditions adopted in this study, the test substace was not readily biodegradable ( 8% DOC removal in 28 days) and showed inhibitory effects (toxicity) to the microbes of activated sludge.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EWG, C.4-C (CO2-Entw.)
- GLP compliance:
- yes
- Inoculum or test system:
- other: Migrated from NONS file.
- Reference substance:
- acetic acid, sodium salt
- Remarks:
- Natriumacetat
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 3.5
- Sampling time:
- 28 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0
- Sampling time:
- 2 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0.8
- Sampling time:
- 9 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 1.5
- Sampling time:
- 14 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 2.9
- Sampling time:
- 27 d
- Details on results:
- A second test was conducted. The second bottle led to a degradation of 2.7% after 28 days.
- Results with reference substance:
- Points of degradation plot (reference substance):14.4 % degradation after 2 d66.8 % degradation after 9 d75.8 % degradation after 14 d84.7 % degradation after 27 d86.7 % degradation after 29 d
- Interpretation of results:
- other: Not readily biodegradable
- Remarks:
- Migrated information criteria used for interepretation of results: EU
- Conclusions:
- For the 28 days study, substance presented a 3.5% degradation (CO2 evolution) meaning that substance was not readily biodegradable.
- Executive summary:
The ready biodegradability of the test susbstance was performed according to 92/69/EWG, C.4-C (CO2-Entw) method.
In this test the degradation of test substance and reference substance were measured the following days (2, 9, 14, 27, 29 d) using as a reference substance sodium acetate. The reference substance at day 28 showed a 86.7% degradation.
In the conditions adopted in this study, the test substace was not readily biodegradable ( 3.5% CO2 evolution in 28 days).
Referenceopen allclose all
Description of key information
Biodegradation in water: screening test. Key study (001).Test method according to OECD 301E. GLP study.The degradation of test substance was measured the following days (1, 4, 7, 14, 21, 28 d) using as a reference substance sodium acetate.
In the conditions adopted in this study, the test substace was not readily biodegradable ( 8% DOC removal in 28 days) and showed inhibitory effects (toxicity) to the microbes of activated sludge
Biodegradation in water: screening test. Key study (002). Test method according to 92/69/EWG, C.4-C (CO2-Entw). GLP study.In this test the degradation of test substance and reference substance were measured the following days (2, 9, 14, 27, 29 d) using as a reference substance sodium acetate.
In the conditions adopted in this study, the test substace was not readily biodegradable ( 3.5% CO2 evolution in 28 days).
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Biodegradation in water: screening test. Key study (001).Test method according to OECD 301E. GLP study. The degradation of test substance was measured the following days (1, 4, 7, 14, 21, 28 d) using as a reference substance sodium acetate. The reference substance at day 28 showed a 98% degradation.
In the conditions adopted in this study, the test substace was not readily biodegradable ( 8% DOC removal in 28 days) and showed inhibitory effects (toxicity) to the microbes of activated sludge
Biodegradation in water: screening test. Key study (002). Test method according to 92/69/EWG, C.4-C (CO2-Entw). GLP study. In this test the degradation of test substance and reference substance were measured the following days (2, 9, 14, 27, 29 d) using as a reference substance sodium acetate. The reference substance at day 28 showed a 86.7% degradation.
In the conditions adopted in this study, the test substace was not readily biodegradable ( 3.5% CO2 evolution in 28 days).
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