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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EPA OPP 72-1 (Fish Acute Toxicity Test)
GLP compliance:
yes
Analytical monitoring:
no
Vehicle:
yes
Details on test solutions:
- Concentration of vehicle in test medium: 0, 0.1, 1.0, 10 100 and 1000 mg/L
Test organisms (species):
Pimephales promelas
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Hardness:
Reconstituted water with total hardness between 40 and 180 mg CsCO3
Test temperature:
22 +- 1C
pH:
Between 6.0 and 8.0
Dissolved oxygen:
At least 60% saturation
Nominal and measured concentrations:
Nominal concentrations of 0.1, 1.0, 10, 100 and 1000 mg/L
Details on test conditions:
TEST SYSTEM
- Test vessel:
- Type open
- Material, fill volume: Glass 1L
- No. of organisms per vessel: 10 fish
- No. of vessels per concentration: 3
- No. of vessels per control: 3
- Biomass loading rate: maximum loading of 0.8g fish/litre
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
29.3 mg/L
Nominal / measured:
nominal
Conc. based on:
act. ingr.
Basis for effect:
mortality (fish)
Remarks on result:
other: 95% CL 25.2-34.1 mg/L
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
10 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Sublethal observations / clinical signs:

A 100% survival rate was observed in the Pimephales promelas treated with 0.1 and 1.0 mg/L. A 97% survival rate was seen in the 10 mg/L concentration group. No fish treated with 100 or 1000 mg/L had survived at the 6 hour observations.

Validity criteria fulfilled:
yes
Conclusions:
In a study performed to EPA OPP 72-1 (Fish Acute Toxicity Test), the 96-hour LC50 of Sodium Cocoyl Methyl Isethionate was 29.3 mg/L with 95% confidence limits of 25.2-34.1 mg/L

Description of key information

In a study performed to EPA OPP 72-1 (Fish Acute Toxicity Test), the 96-hour LC50 of SCMI was 29.3 mg/L

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
29.3 mg/L

Additional information

In a study performed to EPA OPP 72-1 (Fish Acute Toxicity Test, equivalent to OECD 203), the 96-hour LC50 of SCMI was 29.3 mg/L with 95% confidence limits of 25.2-34.1 mg/L