Registration Dossier
Registration Dossier
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EC number: 256-917-3 | CAS number: 51022-74-3
Endpoint summary
Administrative data
Description of key information
No data are available for iotroxic acid (target substance). Thus, iotroxic acid, disodium salt (source substance) is used to assess the aquatic toxicity of iotroxic acid in a read-across approach:
Two trophic levels (Daphnia magna, aquatic algae) are covered by the acute toxicity data set . Chronic data are not available. No adverse effects were observed for both trophic levels (up to 100 and 1000 mg/L)
Additional information
Data describing the acute aquatic toxicity of iotroxic acid is based on read-across from iotroxic acid, disodium salt. In aqueous solution disodium salt disassociates to iotroxic acid.
In an acute immobilization test with Daphnia magna(STRAUS) according to OECD guideline 202, EC guideline Part 2 -Testing Methods, Part C.2 and GLP, the toxic effects of the test item to aquatic invertebrates were determined after 48 h exposure under static conditions. The 48-h EC50was determined to be higher than 1000 mg/L (nominal).
In a 72 hour algal growth inhibition test, cultures of Desmodesmus subspicatus were exposed to iotroxic acid, disodium salt under static conditions in accordance with the OECD Guideline 201 (23 March 2006), EC guideline Part 2 - Testing methods, Part C.3 and under GLP. No inhibition of growth (biomass and growth rate) was observed. The ErC50 (growth rate) was > 100 mg/L (nominal).
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