Diammonium oxalate

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

04 Nov - 04 Dec 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

no

Type of method:

flask method

Water solubility:

41.8 g/L

Conc. based on:

other: Ammonium concentration

Temp.:

20 °C

pH:

6.5

Remarks on result:

other: Mean water solubility measured.

Results
Table 1 – Preliminary Test Results

Amount of test item [mg]	Added volume of distilled water [mL]	Total volume [mL]	Appearance of mixture
92.3	0.1	0.1	Non dissolved
	0.4	0.5
	0.5	1.0
	1.0	2	dissolved

 

From the preliminary tests, the water solubility is ca. 46 g/L. In the main test, water solubility was determined with the flask method.

A further stirring test was performed before the main test, to determine the highest test item concentration that can be sufficiently stirred in a mixture with water.

Table 2 – Stirring test results

Test item amount [mg]	Total vol. of distilled water [mL]	Appearance of mixture
10.11	4	Could not be stirred
	6	Could be stirred

 

After the equilibration time, precipitate was seen in the flaks with the exception of the blank experiment. Water solubility was calculated from measured unrounded concentration values and not from rounded values.

Table 3 – Test item water solubility

Experiment	24 h experiment	48 h experiment	72 h experiment	Blank experiment
Amount of test item [g]	7.12	7.07	7.26	--
Amount of distilled water [mL]	15	15	15	15
Stirring time at 30 °C [h]	24	48	72	72
pH at 23 – 24 °C	6.5	6.6	6.6	6.0
Measured concentration ammonium [g/L]	12.5	12.6	12.5	< 0.0002
Water solubility [g/L]	41.7	42.0	41.7	< 0.0007

 

pH value of blank probe was 6.0, ammonium concentration was < 0.0002 g/L based on measured ammonium content.

The mean water solubility of the test item at 20 °C was determined to be: c_s= 41.8 g/L

Reference 2

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Remarks:

In solubility measurement nio pH value was given

GLP compliance:

not specified

Type of method:

other:

Remarks:

Solid oxalate was dissolved in distilled water. Weighted samples of saturated solution were tritrated by potassium permanganate.

Water solubility:

51.3 g/L

Conc. based on:

not specified

Temp.:

20 °C

Remarks on result:

other: no pH value given, estimated erroro +/- 1%

The water solubity of the test substance is 51.3 g/L at temperature = 20°C.

Reference 3

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Water solubility:

22.7 g/L

Temp.:

20 °C

Remarks on result:

other:

Remarks:

2.27 Weight percent

Reference 4

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Guideline:

other: not given

GLP compliance:

not specified

Water solubility:

45 g/L

Temp.:

20 °C

Description of key information

41.8 g/L at 20 °C (OECD 105, Flask Method)

Key value for chemical safety assessment

Water solubility:

41.8 g/L

at the temperature of:

20 °C

Additional information

Supporting literature data show that water solubility is in the range of 22.7 to 51.3 g/L at 20 °C.