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EC number: 214-490-0 | CAS number: 1135-24-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- 2011
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: publication with no enough detail to allow a conclusion on the reliability. Furthermore the EC50 is expressed as % and this percentage cannot be linked to a concentration in mg/L.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Snails attractant pellets (SAP) were prepared from binary combination of carbohydrate + amino acid (20 mM) in 2% agar solution with active molluscicidal component Ferula asafoetida (ferulic acid, umbelliferone), Syzygium aromaticum (eugenol), Carum carvi (limonene).
The mortality data were observed after every 24h up to 96h. - GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- yes
- Test organisms (species):
- other aquatic mollusc: Lymnaea acuminata
- Details on test organisms:
- Adult L. acuminata (2.25±0.20 cm in length)
- Test type:
- other:
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 1.17 other: %
- Nominal / measured:
- nominal
- Basis for effect:
- mortality
- Details on results:
- The mortality data were observed after every 24h up to 96h. Lethal values (LC50), lower and upper confidence limits (LCL and UCL), slope values, t-ratio, “g” value and heterogeneity factor
were calculated.
The 96h LC50 of different SAP containing umbelliferone (96h LC50- 0.93%), limonene (96h LC50- 0.74%) was higher than of eugenol and ferulic acid 1.03%, 1.17%, respectively. - Validity criteria fulfilled:
- not applicable
- Conclusions:
- The 96h LC50 of different snail attractant pellets (SAP) containing umbelliferone (96h LC50- 0.93%), limonene (96h LC50- 0.74%) was higher than of eugenol and ferulic acid 1.03%, 1.17%, respectively.
- Executive summary:
In this study, the effect of several active molluscicidal component were investigated.
Snails attractant pellets (SAP) were prepared from binary combination of carbohydrate + amino acid (20 mM) in 2% agar solution with active molluscicidal component Ferula asafoetida (ferulic acid, umbelliferone), Syzygium aromaticum (eugenol), Carum carvi (limonene).
The mortality data were observed after every 24h up to 96h.
The 96h LC50 of different snail attractant pellets (SAP) containing umbelliferone (96h LC50- 0.93%), limonene (96h LC50- 0.74%) was higher than of eugenol and ferulic acid 1.03% and 1.17%, respectively.
Reference
Description of key information
Only one study close to the aim of the OECD standard guideline and useful for the REACh requirement hasard assessment was found.
In this study, the molluscicidal effect of the ferulic acid was investigated using Snails attractant pellets (SAP) which were prepared with different active molluscicidal components including ferulic acid. The mortality data were observed after every 24h up to 96h.
The 96h LC50 of different snail attractant pellets (SAP) containing umbelliferone (96h LC50- 0.93%), limonene (96h LC50- 0.74%) was higher than of eugenol and ferulic acid 1.03% and 1.17%, respectively.
In this study, it is not possible to determine the concentration in mg/L of the amount of ferulic acid used. The concentration is expressed as % and this percentage cannot be linked to a concentration in mg/L. Therefore no key value can be determined.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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