Registration Dossier
Registration Dossier
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EC number: 220-180-6 | CAS number: 2654-57-1
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15-05-2017 – 19-05-2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Experimental test result performed using standard test guidelines
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 754.801 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 30 °C
- Remarks on result:
- other: other details not specified
- Details on results:
- The water solubility for the test item 4-methyl-1-phenyl-3-pyrazolidone was found to be 754.801 mg/L at 30°C.
- Conclusions:
- The water solubility determination of test chemical was done by spectrophotometric method and it was determined to be 754.801 mg/L at 30°C.
- Executive summary:
The water solubility determination of test chemical was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 754.801 mg/L at 30°C. Thus the chemical is considered to be moderately soluble in water.
Reference
Table 2:
Sample stirring
|
Concentration obtained on the basis of standard curve |
Dilution factor |
Solubility value obtained (mg/L) |
24 hour |
|
|
|
48 hour |
41.9352 |
20 |
838.704 mg/L |
72 hour |
33.5449 |
20 |
670.898 mg/L |
Considering the water solubility for 48 hrs and 72 hrs the mean water solubility was calculated as follows:
Mean water solubility value for 48 hour run sample + 72 hour run sample
= (838.704+670.898)/2
= 754.801 mg/L
Description of key information
The water solubility determination of test chemical was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 754.801 mg/L at 30°C. Thus the chemical is considered to be moderately soluble in water.
Key value for chemical safety assessment
- Water solubility:
- 754.801 mg/L
- at the temperature of:
- 30 °C
Additional information
The water solubility determination of test chemical was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 754.801 mg/L at 30°C. Thus the chemical is considered to be moderately soluble in water.
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