Registration Dossier
Registration Dossier
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EC number: 255-272-5 | CAS number: 41233-93-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
No studies on skin sensitization with potassium 2-methylbutan-2-olate are available. According to the REACh Regulation (EC) No 1907/2006, Annex VII, column 2 point 8.3 a study on skin sensitization does not need to be conducted if the substance is classified for skin corrosion. The test substance is classified as skin corrosive based on the available information and is used as a transported intermediate. According to REACh regulation 1907/2006, Article 18, further testing is not required.
In contact with water the substance hydrolyses rapidly and forms 2-methylbutan-2-ol and potassium hydroxide. The hydrolysis products 2-methylbutan-2-ol (CAS No. 75-85-4) and potassium hydroxide (CAS No. 1310-58-3) are both not classified as skin sensitizer according to the disseminated dossiers available on the homepage of ECHA and according to Annex VI of the CLP regulation (EC) No 1272/2008.
Migrated from Short description of key information:
Due to animal welfare reasons no test on sensitisation has been conducted as the test substance is corrosive to the skin.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
As the test substance hydrolyses rapidly in contact with water, the hydrolysis products are also considered to be relevant for classification. 2-methylbutan-2-ol (CAS No. 75-85-4) and potassium hydroxide (CAS No. 1310-58-3) showed no sensitizing properties to skin (according to the disseminated dossiers published on the homepage of ECHA) and are not classified as skin sensitizer or respiratory sensitization according to CLP regulation (EC) No 1272/2008. In conclusion, the test substance is not classified as skin sensitizer.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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