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EC number: 241-774-1 | CAS number: 17796-82-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
According to data from biodegradation in water theN-(cyclohexylthio)phthalimide (CTP)is not ready biodegradable.
Additional information from producer - research done with a waste water inoculum after adaptation - shows that CTP is degradable and based on this the biodegradability characteristics in models were defined as “inherently biodegradable”.
The closed bottle test withN-(cyclohexylthio)phthalimide (purity 98.46%)provided after 28 days 34.9 % of biodegradation (Research Institute for Organic Syntheses Inc., 2007b). In the same test method (closed bottle test provided by the same laboratory) withCTP (purity 99.43%)after 10 days 4.2% biodegradation was observed and after 28 days 16 % of the test substance was degraded (Research Institute for Organic Syntheses Inc., 2007c).
If in the toxicity test, containing both the test substance (CTP) and the reference chemicals, less than 25% degradation occurs in 14 days, the test substance could be assumed to be inhibitory. In both closed bottle tests the degradation was more than 25% therefore the CTPis not inhibiting for microorganism in used inoculum.
Ready biodegradability test according to OECD 301 B: Modified Sturm Test was performed with CTP of purity 79.45%.After a period of 28 days a 48 % biodegradation was observed.In the parallel test with CTP and without inoculum the 44% of biodegradation was observed, therefore the main part of observed biodegradation was due to rapid abiotic degradation in water environment (Slovak environmental Agency – COH, 2007).
Contrary result was observed in peer reviewed data from Hazardous Substances Databank (number7259), whereN-(cyclohexylthio)phthalimidewas found to degrade more than 99% after 160 hours in a semi-continuous activated sludge test (primary biodegradation) using adapted sewage (US EPA, 2004), but we have no full data to assess the report.
Chudoba J, et al. (1986)found, thatN-(cyclohexylthio)phthalimideis inhibiting nitrification in wastewater.
According to peer reviewed data from Hazardous Substances Databank (number7259) soil microorganisms were found to not colonize onN-(cyclohexylthio)phthalimidein experiments using soil burial techniques (Williams, 1984).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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