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EC number: 231-831-9 | CAS number: 7758-05-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Short description of key information on bioaccumulation potential result:
The toxicokinetics of potassium iodate have been investigated by H Burgi, etal and the study has been reported in the end point. Following oral administration and intra-arterial infusion, potassium iodate is found to be rapidly absorbed and is excreted predominantly in the urine. Based on the study reported it indicates that there is no potential for bioaccumulation.
Key value for chemical safety assessment
Additional information
Radiolabelled iodate (131I) was administered via i.v. injection to rabbits (no further experimental details available) (Grant, 1974). Radiolabel was absorbed rapidly into aqueous and vitreous humours of the eye (time unknown). Any radiolabel remaining in blood persisted for many hours and was gradually reduced by the liver to iodide. [Klimisch code: 4]
Rats and rabbits (strain unknown) were administered 0.75-1 μg iodine via the oral route or intraperitoneally. Radioiodine was extensively distributed and found in the liver, kidney, brain, heart, muscle, small intestine, stomach, testes, submaxillary gland, skin, hair and thyroid (values unknown). Tissue distribution was the same for both iodine and iodate (Taurog et al., 1966). [Klimisch code: 3]
When added to animal feed, iodate increases the level of iodine in eggs and milk (animal species unknown) (Burgi et al., 2001). No further details are available. [Klimisch code: 4]
Iodate was administered via i.v. injection to rats (dose and strain unknown). Iodate in blood was reduced to iodide within 40 minutes (Burgi et al., 2001). No further details are available. [Klimisch code: 4]
The reduction of iodate has been shown to be a non-enzymatic process and depends on the availability of sulfhydryl groups. It is inhibited by N-ethyl-maleimide (Burgi et al., 2001). No further details are available. [Klimisch code: 4]
Dogs (strain unknown) were fed gelatine capsules containing a single dose of 200 mg potassium iodate/kg bw. Urine from these dogs contained iodide and iodate (Burgi et al., 2001) (no further details are available). This suggests that iodate is converted to iodine (extent unknown) and the urine is a primary route of excretion (extent unknown). [Klimisch code: 4]
Iodate is rapidly absorbed and extensively distributed. It is metabolised via a non-enzymatic process, with a proportion of the available iodate converted to iodine. Iodate is excreted via the kidneys.
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