Registration Dossier
Registration Dossier
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EC number: 204-642-4 | CAS number: 123-68-2
Endpoint summary
Administrative data
Description of key information
Additional information
Valid acute toxicity tests with the test substance are available for three freshwater species from three trophic levels. The studies show that fish is the most sensitive species with a LC50 = 0.117 mg/L (based on geometric mean measured concentrations). In the guideline study over 96 hours under semi-static conditions 100% mortality was observed at 0.219 mg/L and no mortality at 0.0622 mg/L. In a static daphnia study over 48h an EC50 of 2 mg/L was observed. In the valid static algae study the ErC50 after 72 hours was > 4.6 mg/L based on concentration measured on day 0. The ErC10 was determined to be 0.255 mg/L.
The lowest L(E)C50 value of the three studies (Fish LC50 = 0.117 mg/L) is used in the hazard assessment and for derivation of aquatic PNECs.
No test on toxicity to microorganisms is available, but the toxicity control in the available study on ready biodegradability at a nominal concentration of 100 mg/L did not inhibit the microbial activity and the concentration of 100 mg/L can be regarded as a NOEC for inhibition of microorganisms.
No long-term tests on aquatic toxicity are available, but as the risk assessment based on acute toxicity data demonstrated that there is no risk for the aquatic environment, there is no need to investigate further the effects on aquatic organisms.
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