Registration Dossier
Registration Dossier
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EC number: 223-795-8 | CAS number: 4075-81-4
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- no data
- Author:
- Haseltine W.W
- Year:
- 1 952
- Bibliographic source:
- J. Pharm. Pharmac. 4: 120
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- study with volunteers
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Sodium propionate
- EC Number:
- 205-290-4
- EC Name:
- Sodium propionate
- Cas Number:
- 137-40-6
- IUPAC Name:
- sodium propionate
- Details on test material:
- no data
Constituent 1
Method
- Type of population:
- occupational
- Controls:
- no data
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- There was no sensitization response to sodium propionate in trials with human subjects following topical use. The chronic use of 10% sodium propionate solution in clinical trials did not result in sensitization but proved to be hypoallergenic. The substance showed local antihistaminic effects.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
