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EC number: 202-088-8 | CAS number: 91-66-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic/sediments:
Bioaccumulation test was conducted for 8 weeks for determination the bioconcentration factor (BCF) of chemical on testorganism Cyprinus carpio.
Nominal concentrations used in the study are Nominal concentrations 1st Concentration area: 0.2 ppm(v/v), 2nd Concentration area: 0.02 ppm(v/v) and Range finding study was carried out on Rice fish (Oryzias latipes)TLm(48h) 16.8 ppm(w/v). The vehicle used in this study was HCO-40.The bioconcentration factor (BCF) for test chemical was determined in Cyprinus carpio . The BCF value was observed to be in range 44-161 L/kg at dose concentration 0.2 mg/L and 17-125 L/kg at dose concentration 0.02 mg/L on the basis of total lipid content on test organism Cyprinus carpio during 8 weeks period. Therefore it is concluded that this test chemical is nonbioaccumulative.These range BCF values indicate that the test chemical is not bioaccumulative in fish and food chain as these values are far less than 2000 criteria.
Additional information
Bioaccumulation: aquatic/sediments:
Various experimental studies and prediction have been reviewed for test chemical for bioaccumulation endpoint in water endpoint and their results are summarized below.
First study was experimental study reviewed from authoritative database ( J -check) in this study the bioaccumulation test was conducted for 8 weeks for determination the bioconcentration factor (BCF) of chemical on test organism Cyprinus carpio. Nominal concentrations used in the study are Nominal concentrations 1st Concentration area: 0.2 ppm(v/v), 2nd Concentration area: 0.02 ppm(v/v) and Range finding study was carried out on Rice fish (Oryzias latipes) TLm(48h) 16.8 ppm(w/v). The vehicle used in this study was HCO-40.The bioconcentration factor (BCF) for test chemical was determined in Cyprinus carpio . The BCF value was observed to be in range 44-161 L/kg at dose concentration 0.2 mg/L and 17-125 L/kg at dose concentration 0.02 mg/L on the basis of total lipid content on test organism Cyprinus carpio during 8 weeks period. Therefore it is concluded that this test chemical is nonbioaccumulative. These range BCF values indicate that the test chemical is non bioaccumulative in fish and food chain as these values are far less than 2000 criteria.
Another study was reviewed from Ecotoxicology and Environmental Safety journal (1980) in this study the BCF value of test chemical was estimated by using equation taken from Kenaga and Goring (1978). The bioaccumulation concentration factor of test chemical was estimated to be 16 dimensionless by using water solubility of test chemical. On the basis of BCF value it is concluded that test chemical is non bioaccumulative in nature.
In last study prediction was done by using BCFBAF Program (v3.00) model of EPI suite (2018) the estimated bio concentration factor (BCF) for test chemical is 70.95 L/kg wet-wt at 25 deg. c which does not exceed the bioconcentration threshold of 2000. Therefore it is concluded that test chemical is non-bioaccumulative in food chain.
By considering results of all the studies mentioned above it is concluded that BCF value of test chemical is in range of 16-161 L/Kg this range BCF value indicates that test chemical is non bioaccumulative in nature.
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