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EC number: 473-390-7
CAS number: -
The acute oral toxicity of FC-770 (liquid, batch 142072-43) was assessed
in female 9 week old Wistar rats following OECD guideline No. 423
(2001), “Acute Toxicity-Oral, Acute Toxic Class Method.” Five animals
were given a single undiluted oral gavage dose of 2000 mg/kg body
weight. One additional animal was inadvertently dosed at 1875 mg/kg body
weight. The results from this inadvertent dose were consistent with the
2000 mg/kg dose group and for the purposes of this study that animal was
considered as receiving the 2000 mg/kg dose. Animals were observed daily
for 15 days. Body weights were recorded on day 1, 8 and 15. A necropsy
was performed on day 15. Hunched posture and piloerection were observed
on day 1 after dose administration. There were no abnormalities in
remaining clinical observations, body weight and macroscopic post mortem
examination. The oral LD50 of FC-770 in Wistar rats was >2000 mg/kg body
weight. According to the OECD 423 test guideline the LD50 cut-off value
was considered to exceed 5000 mg/kg body weight. Based on these results
FC-770 does not have to be classified and has no obligatory labeling
requirement for oral toxicity according to the Globally Harmonized
System of Classification and Labeling of Chemicals (GHS) of the United
Nations and EC criteria for classification and labeling requirements for
dangerous substances and preparations (Council Directive 67/548/EEC).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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