Chloroacetone

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 2020-05-11 to 2020-06-30

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

2008

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

>= -41 - <= -39 °C

Atm. press.:

>= 1 021 - <= 1 022 hPa

Decomposition:

no

Sublimation:

no

Measurement No.	Sample weight / mg	Onset of Effect / °C	Range of effect / °C	Weight loss / mg	Atmospheric pressure / hPa
PN19750	11.19	---	-80 (exo)	11.19	1021.6
		-41.28 119.86	-50 to -30 (endo) 100 – 130 (endo)
PN19751	10.34	---	-70 (exo)	10.34	1021.3
		-39.32 120.41	-50 to -30 (endo) 100 – 130 (endo)

During the heating phase a distinct endothermic effect was observed in the temperature range of -50 to -30 °C which can be assigned to the melting of the test item.

As the onset temperatures in both tests deviate by more than 0.5 K from their mean value of -40.30 °C, a temperature range is specified as melting range of the test item. The test item has a melting range of -41 to -39 °C.

The test item showed a second endothermic effect in the temperature range of 100 – 130 °C which can be assigned to the boiling of the test item. No further thermal effects were observed up to the test end temperature of 500 °C.

Conclusions:

The test item has a melting range of -41 °C to -39 °C at atmospheric pressure (1021 – 1022 hPa) as determined by differential scanning calorimetry.

Executive summary:

A study was conducted according to Regulation (EC) No 440/2008 Method A.1. and OECD Test Guideline 102 (1995). The melting point was determined by differential scanning calorimetry (DSC). The test item was cooled down to -90 °C and then heated up to 500 °C at a constant heating rate of 10 K/min under air. During the heating phase a distinct endothermic effect was observed in the temperature range of -50 to -30 °C which can be assigned to the melting of the test item. As the onset temperatures in both tests deviate by more than 0.5 K from their mean value of -40.30 °C, a temperature range is specified as melting range of the test item. The test item has a melting range of -41 to -39 °C. The test item has a melting range of -41 °C to -39 °C at atmospheric pressure (1021 – 1022 hPa).

Description of key information

The test item has a melting range of -41 °C to -39 °C at atmospheric pressure (1021 – 1022 hPa) as determined by differential scanning calorimetry (reference 4.2-1).

Additional information

A study was conducted according to Regulation (EC) No 440/2008 Method A.1. and OECD Test Guideline 102 (1995). The melting point was determined by differential scanning calorimetry (DSC). The test item was cooled down to -90 °C and then heated up to 500 °C at a constant heating rate of 10 K/min under air. During the heating phase a distinct endothermic effect was observed in the temperature range of -50 to -30 °C which can be assigned to the melting of the test item. As the onset temperatures in both tests deviate by more than 0.5 K from their mean value of -40.30 °C, a temperature range is specified as melting range of the test item. The test item has a melting range of -41 to -39 °C. The test item has a melting range of -41 °C to -39 °C at atmospheric pressure (1021 – 1022 hPa).