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Diss Factsheets
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EC number: 949-117-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25-Jul to 02-Aug-2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: Due to the complex nature and composition of the test item, the water solubility was expressed in terms of the critical micelle concentration (CMC).
- Version / remarks:
- EU Method A.5 (surface tension)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: Due to the complex nature and composition of the test item, the water solubility was expressed in terms of the critical micelle concentration (CMC).
- Version / remarks:
- OECD 115 (surface tesnion)
- GLP compliance:
- no
- Type of method:
- other: EU Method A.5 and OECD 115; water solubility expressed in terms of the critical micelle concentration.
- Water solubility:
- 49 mg/L
- Temp.:
- 20 °C
- pH:
- > 5.8 - < 7.6
Reference
Results
The concentration (mg/L), log10 [concentration (mg/L)] and mean surface tension values for the sample solutions are shown in the following table:
Concentration (mg/L) |
Log10 Concentration |
Mean Surface Tension (mN/m) |
Solution pH |
5.021 x 103 |
3.701 |
36.5 |
7.6 |
1.004 x 103 |
3.002 |
37.5 |
6.9 |
301.2 |
2.479 |
38.7 |
6.4 |
100.4 |
2.002 |
40.7 |
6.0 |
30.12 |
1.479 |
44.2 |
5.8 |
10.04 |
1.002 |
52.2 |
5.9 |
3.012 |
0.479 |
62.7 |
5.8 |
1.004 |
0.002 |
66.5 |
5.8 |
0.3012 |
-0.521 |
70.5 |
5.8 |
0.1004 |
-0.998 |
72.0 |
5.8 |
The results were used to plot log10 [concentration (mg/L)] versus surface tension (mN/m).
Line 1 was generated from linear regression of 3 sample solution concentrations for which the surface tension was shown to be concentration dependent and Line 2 was generated from linear regression of 2 sample solution concentrations for which the surface tension was observed to be essentially independent of concentration. The intersection of
these two lines gave the critical micelle concentration and was calculated by solving the two equations:
Line1 equation: y = -18.5x+71.3
Line 2 equation: y = -1.78x +43.0
The sample solution at 100.4 mg/L was not used in generating the two lines. At this concentration the surface tension appeared to be transitioning to Line 2 at a shallower gradient than Line 1.
The sample solutions at 1.004, 0.3012 and 0.1004 mg/L were not used in generating the two lines. At this concentration the surface tension was only slightly affected and was approaching that of purified water.
The CMC was determined to be 48.9 mg/L.
Discussion
The critical micelle concentration (CMC) is an important characteristic of a surfactant. At low concentrations of surfactant, the surface tension of water is only slightly affected. Increasing the concentration but before reaching the CMC, the surface tension changes significantly. After reaching the CMC and above, the surface tension remains relatively constant or changes with a much more gradual slope.
Below the CMC, a surfactant is considered to be thermodynamically soluble in the water; whereas above the CMC, the solubility of a surfactant in water has been exceeded and the excess surfactant aggregates to form micelles. These micelles have significantly less effect on the surface tension of a solution and are considered not to be in solution. Thus, the water solubility of a surfactant may be expressed in terms of the CMC.
Conclusion
The critical micelle concentration of the test item was determined to be 49 mg/L at 20.0 ± 0.5 °C.
Description of key information
49 mg/L at 20 °C (critical micelle concentration (CMC) determination, OECD 115)
Key value for chemical safety assessment
- Water solubility:
- 49 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.