Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-252-7 | CAS number: 136-60-7
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
An evaluation of the inherent properties of butyl benzoate is performed against the ANNEX XIII criteria. If insufficient data were available, the screening criteria as laid down in ECHA Guidance on information requirements and chemical safety assessment Chapter R.11: PBT Assessment (2014) were applied.
The persistency assessment is based on the screening criteria in Annex XIII of the REACH Regulation. The biodegradation potential of the test substance has been assessed in a guideline study on ready biodegradability following the OECD 301B (IES, 2018). A 28-d ready biodegradability test (OECD 301F) using unadapted activated sludge from a predominantly domestic waste water treatment plant indicated that butyl benzoate was readily biodegradable under the conditions of the test (initial concentration 100 mg/L). The test substance showed 74% biodegradation (test bottle 1 and 2, respectively, based on % ThCO2). It can therefore be concluded that based on the criteria mentioned above the substance is not persistent in the environment. The substance is concluded to be not P/vP.
The bioaccumulation assessment is based on the screening criteria in Annex XIII of the REACH Regulation.The available evidence on the bioaccumulation potential for the substance indicates that the screening criteria for bioaccumulation potential (B and vB) are not met. Based on a log Pow of 3.30 at neutral pH, a low BCF can be estimated. Since the log Pow of the substance is < 4.5, the screening criteria for bioaccumulation are not fulfilled and the substance is concluded not to have a bioaccumulative potential (not B / not vB).
The toxicity assessment is based on the screening criteria in Annex XIII of the REACH Regulation. Based on an OECD 201 study (Envigo, 2018) it is concluded that the test item does not meet the Toxic (T) criteria since the EC10 was 1.5 mg/L. The test substance is not classified as carcinogenic (Cat. 1 or 2), as mutagenic (Cat. 1 or 2), or as reproductive toxicant (Cat. 1, 2, or 3), nor as STOT RE Cat. 1 or 2 according to the Regulation EC N° 1272/2008. Hence, it does not fulfill the criteria to be considered as Toxic (not T).
Taking into account the conclusions that the substance is not P/vP, not B/vB and not T, the substance should not be considered as a PBT/vPvB substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
