Registration Dossier

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
not specified
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Final Report on the Safety Assessment of Sodium Iodate
Author:
Cosmetic Ingredient Review (Expert Panel)
Year:
1995
Bibliographic source:
Journal of the American College of Toxicology 14(3):231-239, Raven Press, Ltd., New York

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
An Ames test was conducted with the substance
GLP compliance:
not specified
Type of assay:
bacterial reverse mutation assay

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Test results
Key result
Species / strain:
not specified
Metabolic activation:
not specified
Genotoxicity:
negative
Cytotoxicity:
not specified
Vehicle controls valid:
not specified
Negative controls valid:
not specified
Positive controls valid:
not specified

Applicant's summary and conclusion

Conclusions:
The test material showed no mutagenic activity by the Ames test.
Executive summary:

The test material showed no mutagenic activity by the Ames test.