Registration Dossier

Classification & Labelling & PBT assessment

PBT assessment

Administrative data

PBT assessment: overall result

Reference
Name:
Methylcyclopentane
Type of composition:
boundary composition of the substance
State / form:
liquid
Reference substance:
Composition 1
PBT status:
the substance is not PBT / vPvB
Justification:

PBT/vPvB criteria and justification

Persistence (P) Assessment:

A substance is not considered to be persistent if it can be demonstrated that it has potential to degrade (via photolysis, hydrolysis and/or biodegradation).

There is no data available for methylcyclopentane. Data is available for Hydrocarbons, C6, isoalkanes, <5% n-hexane and n-hexane and this data is used for read across to methylcyclopentane. An OECD 301F Manometric Respirometry test was conducted using C6-C7, n-alkanes, isoalkanes, cyclics C6 aliphatics. The test substance was 98% degraded at the end of 28 days, and 83% degraded at the end of the 10 -day window. The substance is therefore considered to be readily biodegradable. Therefore, methylcyclopentane does not meet the Persistent (P) or very Persistent (vP) criteria.

Bioaccumulation (B) Assessment:

An evaluation of representative hydrocarbon structures indicates no structures meet the Bioaccumulative (B) or very Bioaccumulative (vB) criteria (CONCAWE 2010a).

Therefore, based on the screening criteria for bioaccumulation stipulated in the ECHA’s Guidance on information requirements and chemical safety assessment - Part C: PBT Assessment (2008), methylcyclopentane is considered unlikely to be bioaccumulative.

Toxicity (T) Assessment:

Environmental Toxicity:

No representative structures were identified as PBT or vPvB, therefore a toxicity assessment is not needed. None of the measured or calculated data for methylcyclopentane, is within the criteria for toxicity stipulated in the ECHA’s Guidance on information requirements and chemical safety assessment - Part C: PBT Assessment (2008). Therefore this substance is not considered toxic (T).

Human Health Hazards Assessment (T)

Carcinogenicity:

The available data on methylcyclopentane do not warrant classification for carcinogenicity under Dir 67/548/EEC or GHS/CLP.

Mutagenicity:

The available data indicate that methylcyclopentane is not genotoxic or mutagenic and do not warrant classification for carcinogenicity under Dir 67/548/EEC or GHS/CLP.

Reproductive Toxicity:

There is no evidence that methylcyclopentane causes reproductive or developmental toxicity. The available data indicate that members of the C7-C9 aliphatic hydrocarbon solvent category are not toxic to reproduction and do not warrant classification under Dir 67/548/EEC or GHS/CLP.