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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
September 27th, 2016.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reference:
Composition 0
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: Knudsen cell
Test material information:
Composition 1
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0 Pa

The vapour pressure of the test item at 20ºC and 25ºC was calculated on the basis of the equation log (p) = f (1/t) = a-b/(t+273.15), where: p – vapour pressure in Pa, t – temperature in ºC, obtained for four measurement points: 137.3ºC, 142.6ºC, 148.7ºC and 154.1ºC.


Table 1. The determined vapour pressure is:

Test sample

Vapour pressure
at 20 ºC

Vapour pressure
at 25 ºC

Neohesperidin dihydrochalcone

6.13·10-11Pa

1.94·10-10Pa



Conclusions:
The vapour pressure of the test item is 6.63E-11 Pa at 20ºC and 1.94E-10 Pa at 25ºC.
Executive summary:

The study of the vapour pressure using effusion method was performed in accordance with the method EU A4 - Knudsen cell (GLP study). The vapour pressure of the test item is 6.63E-11 Pa at 20ºC and 1.94E-10 Pa at 25ºC.

Description of key information

Key study. Method according to EU Method A.4, GLP study. The vapour pressure of the test item is 6.63E-11 Pa at 20ºC and 1.94E-10 Pa at 25ºC.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information

The study of the vapour pressure using effusion method was performed in accordance with the method EU A4 - Knudsen cell (GLP study). The vapour pressure of the test item is 6.63E-11 Pa at 20ºC and 1.94E-10 Pa at 25ºC.