Registration Dossier
Registration Dossier
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EC number: 205-622-8 | CAS number: 144-29-6
pH
Administrative data
- Endpoint:
- pH
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Experimental test result performed using standard OECD test guidelines
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 122(pH measurement interface Microlab FS-524 and pH probe)
- Principles of method if other than guideline:
- The pH of an aqueous solution or dispersion in water is determined with a pH measurement interface equipped with an appropriate electrode system.
- GLP compliance:
- no
Test material
- Reference substance name:
- Tripiperazine dicitrate
- EC Number:
- 205-622-8
- EC Name:
- Tripiperazine dicitrate
- Cas Number:
- 144-29-6
- Molecular formula:
- C6H8O7.3/2C4H10N2
- IUPAC Name:
- piperazine 2-hydroxypropane-1,2,3-tricarboxylate (3:2) (salt)
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): Piperazine Citrate - Molecular formula: C12H30N6•Cl2H16O14 - Molecular weight: 642.76 g/mole - Smiles notation: C1CNCCN1.C1CNCCN1.C1CNCCN1.C(C(=O)O)C(CC(=O)O)(C(=O)O)O.C(C(=O)O)C(CC(=O)O)(C(=O)O)O - Substance type: Organic - Physical state: Solid-Purity:99.0% (BP)
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Piperazine citrate / tripiperazine dicitrate- Molecular formula: C12H30N6•Cl2H16O14 - Molecular weight: 642.76 g/mole - Substance type: Organic - Physical state: Solid
Results and discussion
pH value
- Key result
- pH value:
- 5.6
- Temp.:
- 26.5 °C
- Concentration:
- 1 other: % w/v
- Remarks on result:
- other: Acidic in nature
Any other information on results incl. tables
Temperature of 1% w/v test solution | - | 26.5°C |
pH (RESULT)
| - | 5.60 |
Inference | 1. Acidic 2. Basic 3. Neutral
| Acidic |
Applicant's summary and conclusion
- Conclusions:
- The pH determination of test item Tripiperazine dicitrate (CAS No. 144-29-6) was done following OECD guideline 122. pH of 1% w/v aqueous solution was measured with the help of pH meter/probe and it was observed to be 5.60 at 26.5 °C.
- Executive summary:
The pH determination of test item Tripiperazine dicitrate(CAS No. 144-29-6) was done as per the test guideline OECD 122. The pH of the test solution was determined with the help of pH probe. The measurement interface was Micro Lab FS-524; software version 6.2 8b. The pH was found to be 5.60 at 26.5°C.
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