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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
Principles of method if other than guideline:
The partition coefficient was estimated by measuring the solubility of the test substance in the pure solvents.
GLP compliance:
no
Type of method:
calculation method (fragments)
Partition coefficient type:
octanol-water
Analytical method:
liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
-1.11
Temp.:
25 °C
pH:
>= 5.1
Details on results:
The Log kow of Guanidine thiocyanate is calculated to be -1.11 based on solubility in n-octanol and water.
Conclusions:
The Log kow of Guanidine thiocyanate is calculated to be -1.11 based on solubility in n-octanol and water at 25 °C.

Description of key information

The Log kow of Guanidine thiocyanate is calculated to be -1.11 based on solubility in n-octanol and water at 25 °C.

Further, the log Kow was estimated to be -4.04 using QSAR (KOWWIN 1.67)

The calculated value of -1.1 based on solubility in n-octanol and water was used for safety assessment.

Key value for chemical safety assessment

Log Kow (Log Pow):
-1.1
at the temperature of:
25 °C

Additional information