Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 240-032-4 | CAS number: 15894-70-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity test results with algae (Pseudokirchnerella subcapitata) resulted in 72-hr EC50 = 17mg/L, based on growth and 72-hr NOEC = 2.5mg/L, based on growth.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 17 mg/L
- EC10 or NOEC for freshwater algae:
- 2.5 mg/L
Additional information
A reliable (Klimisch 1) toxicity study with algae has been conducted with HMBDA and is included in this dossier.
Smyth et al. (1993) conducted a reliable (Klimisch 1) GLP compliant study according to OECD 201 methods.Selenastrum capricornutum(new name:Pseudokirchnerella subcapitata) were exposed to measured concentrations (0.59, 1.3, 2.5, 4.7, 9.1, 15, 20, 25 mg/l) of HMBDA for 72 hours in a static system.The 72-hr EC50, based on growth, was 17 mg/L. The 72-hr NOEC, based on growth, was 2.5 mg/L.
Adequate reliable measured data exists for toxicity of HMBDA to algae. The data point of highest concern for this endpoint has been identified in a reliable study which reports a measured 72 hr EC50 of 17 mg/L and 72 hr NOEC of 2.5 mg/L, based on growth, for toxicity to aquatic algae. Consequently these values will be taken as the toxicity in aquatic algae endpoint for HMBDA.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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