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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Acute oral toxicity: Key study: The oral LD50 in male rats was 3.25 (2.48-4.26) g/kg bw (no specific test guideline was reported).
Acute inhalation toxicity: Key study: Read-across from experimental data on the category analogue Calcium acetate. The LC50 for substance Potassium Acetate is calculated to be higher than 6.95 mg/L air under test conditions.
Acute dermal toxicity: Key study: Read-across from experimental data on the analogue Fumaric Acid. The LD 50 for Potassium Acetate is calculated to be greater than 33820.97 mg/kg bw under test conditions.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
3 250 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
6 950 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
33 820.97 mg/kg bw

Additional information

Acute oral toxicity:

Key study:

Experimental results: No specific test guideline was reported; however, a scientifically defensible approach was used to conduct the study. The oral LD50 of Potassium acetate in male rats was 3.25 (2.48-4.26) g/kg bw.

Acute inhalation toxicity:

Key study:

Experimental results from a study similar to OECD 403 on the category analogue Calcium Acetate. The LC50 value for 4 hours exposition at rat (male and female) is higher than 5.6 mg/L.

Based on this experimental result and the molecular weights, the read-across approach is applied and the LC50 for substance Potassium Acetate is calculated to be higher than 6.95 mg/L air under test conditions.

Acute dermal toxicity:

Key study:

Experimental results from a study similar to OECD 402 on the analogue Fumaric Acid. The LD50 for Fumaric Acid is higher than 20000 mg/kg bw for rabbits.

Based on this experimental result and the molecular weights, the read-across approach is applied and the LD 50 for Potassium Acetate is calculated to be greater than 33820.97 mg/kg bw under test conditions.

Justification for classification or non-classification

Acute toxicity:

Oral: LC50>2000mg/kg bw: non- classification

Dermal: LC50>2000mg/kg bw: non- classification

Inhalation: LC50>5 mg/L: non-classification