Registration Dossier
Registration Dossier
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EC number: 231-749-3 | CAS number: 7719-12-2
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
One published paper is available, which summarises the results of studies of sperm morphology in the rat (inhalation exposure) and mouse (gavage exposure).
Additional information
No information is available.
Effects on developmental toxicity
Description of key information
One published paper is available, which summarises the results of a developmental toxicity study in the rat.
Effect on developmental toxicity: via oral route
- Dose descriptor:
- NOAEL
- 178 mg/kg bw/day
Effect on developmental toxicity: via inhalation route
- Dose descriptor:
- NOAEC
- 97.76 mg/m³
Additional information
No evidence of developmental toxicity or teratogenicity was seen in a study in the rat at the highest dose level of 19.3 mg/kg bw.
Toxicity to reproduction: other studies
Additional information
No effects on sperm morphology are apparent in studies in the rat and mouse.
Justification for classification or non-classification
Phosphorus trichloride is not classified for reproductive or developmental toxicity according to Directive 67/548/EEC. No classification is proposed, based on the results of the data summarised.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
