Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
health surveillance data
Type of information:
other: case study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: PCl3 mentioned without detailed evidence

Data source

Reference
Reference Type:
publication
Title:
Bronchial asthma and asthmatic bronchitis in the chemical industry
Author:
Lerner R
Year:
1955
Bibliographic source:
Ind. Med. Surg. 24, 454-458

Materials and methods

Study type:
human medical data
Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Case study
GLP compliance:
no
Remarks:
: not relevant

Test material

Constituent 1
Chemical structure
Reference substance name:
Phosphorus trichloride
EC Number:
231-749-3
EC Name:
Phosphorus trichloride
Cas Number:
7719-12-2
Molecular formula:
Cl3P
IUPAC Name:
phosphorus trichloride

Method

Details on study design:
Assessment of health effects in exposed workers

Results and discussion

Results:
An increased incidence of asthma is reported in workers occupationally exposed to PCl3.

Applicant's summary and conclusion

Conclusions:
An increased incidence of asthma is reported in workers occupationally exposed to PCl3.
Executive summary:

The authors report an increased incidence of 'asthma 'in workers occupationally exposed to PCl3, however it is unclear whether the effects represent true asthma (respiratory sensitisation) or an irritant effect.