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EC number: 202-180-8 | CAS number: 92-70-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1992
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: All information on this study, including the reliability grade, is derived from OECD SIDS 3-hydroxy-2-naphthoic acid CAS: 92-70-6 dated 2004-11-23, as the complete study report is not at hand.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- OECD SIDS 3-Hydroxy-2-naphthoic acid CAS: 92-70-6
- Author:
- OECD
- Year:
- 2 004
- Bibliographic source:
- OECD SIDS 3-Hydroxy-2-naphthoic acid CAS: 92-70-6, UNEP Publications 2004: 1-72, Ref 16
- Report date:
- 2004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
- Deviations:
- no
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-hydroxy-2-naphthoic acid
- EC Number:
- 202-180-8
- EC Name:
- 3-hydroxy-2-naphthoic acid
- Cas Number:
- 92-70-6
- Molecular formula:
- C11H8O3
- IUPAC Name:
- 3-hydroxynaphthalene-2-carboxylic acid
Constituent 1
- Radiolabelling:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Cyprinus carpio
Study design
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 42 d
Test conditions
- Nominal and measured concentrations:
- Nominal concentrations: 0.1 mg/L and 1 mg/L
Results and discussion
Bioaccumulation factoropen allclose all
- Type:
- BCF
- Value:
- < 4
- Basis:
- not specified
- Remarks on result:
- other: Conc.in environment / dose:0.1 mg/L
- Type:
- BCF
- Value:
- < 0.5
- Basis:
- not specified
- Remarks on result:
- other: Conc.in environment / dose:1 mg/L
Depuration
- Elimination:
- not specified
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- Regarded as valid since no opposite statement was done in OECD-SIDS. Criteria for water parameters fulfilled (oxygen concentration ≥60% saturation, temperature variation less than ± 2°C). No data on test concentrations and on survival of fish at test end.
- Conclusions:
- 3-hydroxy-2-naphthoic acid showed no potential for bioaccumulation (BCF <4).
- Executive summary:
The potential of 3-hydroxy-2-naphthoic acid to bioaccumulate of was determined in a 42-d bioaccumulation study in accordance with OECD Guideline 305 C. Tested concentrations were 0.1 and 1 mg/L. No information about GLP-compliance was available. Compliance with the validity criteria could not be verified. Reliability grade 2 was assigned. The bioconcentration factor (BCF) of 3-hydroxy-2-naphthoic acid was <4 and <0.5 (at concentrations of 0.1 and 1 mg/L, respectively).
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