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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Range-Finding Toxicity Data: List IV
Author:
Smyth H, Carpenter CP, Weil CS
Year:
1951
Bibliographic source:
AMA Arch . Ind . Hyg . Occ . Med . 9 :119-122.

Materials and methods

Principles of method if other than guideline:
Not specified
GLP compliance:
not specified
Test type:
other: Not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Bis(2-ethylhexyl) adipate
EC Number:
203-090-1
EC Name:
Bis(2-ethylhexyl) adipate
Cas Number:
103-23-1
Molecular formula:
C22H42O4
IUPAC Name:
bis(2-ethylhexyl) adipate
Details on test material:
CAS no: 103-23-1
Lot no: LDJ4348
Purity: 99.8%
Supplier: Wako Pure Chemical Industries (Tokyo, Japan)

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
Vehicle:
not specified
Details on inhalation exposure:
air saturated with DEHA
Duration of exposure:
8 h

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LC0
Effect level:
other: air saturated
Based on:
test mat.
Exp. duration:
8 h
Remarks on result:
other: no mortality to rats exposed to air saturated with DEHA for 8 hours

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
Data for acute inhalation exposure are limited, but available information shows no mortality to rats exposed to air saturated with DEHA for 8 hours