Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 211 (Daphnia magna Reproduction Test)
GLP compliance:
no
Analytical monitoring:
yes
Test organisms (species):
Daphnia magna
Details on test organisms:
Feed: Chlorella vulgaris
Age of the animals at the start: <24 h
Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
21 d
pH:
8.0
Dissolved oxygen:
>9mg/L
Key result
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
ca. 0.002 mg/L
Nominal / measured:
meas. (initial)
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
0.003 mg/L
Nominal / measured:
meas. (initial)
Basis for effect:
reproduction
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.005 mg/L
Nominal / measured:
meas. (initial)
Basis for effect:
other: First appearance of young
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
0.006 mg/L
Nominal / measured:
meas. (initial)
Basis for effect:
reproduction
Remarks on result:
other: diluted in acetone
Duration:
21 d
Dose descriptor:
LC50
Effect conc.:
0.2 mg/L
Nominal / measured:
meas. (initial)
Basis for effect:
mortality

In a Study performed to OECD Guideline 211 ferrocene produced these results: NOEC (reproduction) = ca. 0.0015 mg/L, NOEC (first appearance of young) = 0.005 mg/l, LC50 = 0.2 mg/l

Daphnia magna appear to be very sensitive to ferrocene regarding effects on reproduction. The high sensitivity in terms of the reproduction of daphnia magna may suggest a specific effect of ferrocene

Validity criteria fulfilled:
yes
Conclusions:
In a Study performed to OECD Guideline 211 ferrocene produced these results: NOEC (reproduction) = ca. 0.0015 mg/L, NOEC (first appearance of young) = 0.005 mg/l, LC50 = 0.2 mg/l

Daphnia magna appear to be very sensitive to ferrocene regarding effects on reproduction. The high sensitivity in terms of the reproduction of daphnia magna may suggest a specific effect of ferrocene

Description of key information

In a Study performed to OECD Guideline 211 ferrocene acheived these results:


NOEC (reproduction) = ca.0.0015 mg/L, NOEC (first appearance of young) = 0.005 mg/l, LC50 = 0.2 mg/l

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Dose descriptor:
NOEC
Effect concentration:
0.002 mg/L

Additional information

In a Study performed to OECD Guideline 211 ferrocene produced these results: NOEC (reproduction) = ca. 0.0015 mg/L, NOEC (first appearance of young) = 0.005 mg/l, LC50 = 0.2 mg/l

Daphnia magna appear to be very sensitive to ferrocene regarding effects on reproduction. The high sensitivity in terms of the reproduction of daphnia magna may suggest a specific effect of ferrocene on daphnia.