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Diss Factsheets

Physical & Chemical properties

Vapour pressure

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Administrative data

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1994
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Reliability rating is 1 because the data were determined using standard 92/69/EEC Method A4 vapor pressure and was carried out under GLP.
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Principles of method if other than guideline:
Effusion method: isothermal thermogravimetry using a vapor pressure balance. The method is based on the determination of accelerated evaporation rates for the test substance at elevated temperatures and ambient pressure using thermogravimetry. The evaporation rates vT result from exposing the selected compound to a slowly flowing inert gas atmosphere, and monitoring the weight loss at defined isothermal temperatures T in Kelvin over appropriate periods of time. The vapour pressures pT are estimated from the vT values by using the linear relationship between the logarithm of the vapour pressure and the logarithm of the evaporation rate. An extrapolation to temperatures of 25°C can be made by regression analysis of log pT vs. 1/T.
GLP compliance:
yes
Type of method:
effusion method: vapour pressure balance
Temp.:
25 °C
Vapour pressure:
0 Pa
Remarks on result:
other: The vapor pressure of the test substance was estimated to be 4.2 x 10-4 Pa at 25°C.
Conclusions:
The vapor pressure of the test substance was estimated to be 4.2 x 10-4 Pa at 25°C. The vapor pressure balance or effusion method is an acceptable method for substances with a relatively low vapor pressure.
Executive summary:

The vapor pressure of the test substance was estimated to be 4.2 x 10-4 Pa at 25°C.

Description of key information

The vapor pressure of the test substance was estimated to be 4.2 x 10-4 Pa at 25°C. The vapor pressure balance or effusion method is an acceptable method for substances with a relatively low vapor pressure.

Key value for chemical safety assessment

Additional information