Registration Dossier
Registration Dossier
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EC number: 220-357-8 | CAS number: 2736-18-7
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 03-1998 to 04-1998
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
- Report date:
- 1998
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- GLP compliance:
- yes
- Test type:
- acute toxic class method
Test material
- Reference substance name:
- 4,6-dichloro-1,3,5-triazin-2(1H)-one, sodium salt
- EC Number:
- 220-357-8
- EC Name:
- 4,6-dichloro-1,3,5-triazin-2(1H)-one, sodium salt
- Cas Number:
- 2736-18-7
- Molecular formula:
- C3HCl2N3O.Na
- IUPAC Name:
- 4,6-dichloro-1,3,5-triazin-2(1H)-one, sodium salt
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- water
- Doses:
- single dose 2000mg/kg
- No. of animals per sex per dose:
- 3 animals
Results and discussion
Effect levels
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD0
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- 95% CL:
- ca. 100
- Mortality:
- none
- Clinical signs:
- other: none
- Gross pathology:
- no abnormalites detected
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- 4,6-dichloro-1,3,5-triazin-2(1H)-on sodium salt does not show any mortality at a dose of 2000 mg/kg bw. No classification is necessary.
- Executive summary:
A study according to OECD 423 was performed.
With a dose of 2000mg/kg bw, administred orally to three male and three female rat there were no deaths.There wer no clinical signs of toxicity
All animals showed expected gains in bodyweight.
No abnomalities were noted at necropsy.
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