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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 810-495-2 | CAS number: 93452-03-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Studies Klimisch rated reliability 2 based on international guidelines are available for three aquatic trophic levels (algae, aquatic invertebrate and fish) on an analogue substance, METHYL 3-OXO-2-PENTYL-1-CYCLOPENTANE ACETATE (quality High Trans isomer). This read-across substance is a mixture of two diastereomers, approximately 10% cis- and 90% trans-diastereomers of which the cis-diastereomer corresponds to the registered substance. This supporting substance is considered adequate for read-across purposes based on similar physico-chemical properties and readily biodegradability of the registered substance and the analogue material used (see IUCLID section 13).
Among all data available, the aquatic invertebrate, Daphnia magna, is the most sensitive species with a 48h-EC50 at 8.25 mg/L. A chronic toxicity data is also available with a 21d-EC10 for reproduction at 1.86 mg/L. On the fish Oryzias latipes, the 96h-LC50 was determined to be 19 mg/L, and on the algae Pseudokirchneriella subcapitata, the 72h-ErC50 and NOECr (based on growth rate) were determined to be 45.9 mg/L and 11.7 mg/L, respectively. Due to the lower sensitivity of the fish compared to that of the daphnids, a fish chronic study was not considered necessary.
In addition, there is no need to perform an activated sludge inhibition test, in accordance with column 2 of REACH Annex VIII, because the substance is readily biodegradable. The applied test concentration in the key biodegradation study (101 mg/L) is in the range of concentrations that can be expected in the influent of a sewage treatment plant, and no inhibition effects on the activity of microorganisms was observed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.