Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Reference not available, secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
1978

Materials and methods

Type of sensitisation studied:
skin
Study type:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Disulfiram
EC Number:
202-607-8
EC Name:
Disulfiram
Cas Number:
97-77-8
Molecular formula:
C10H20N2S4
IUPAC Name:
disulfiram

Method

Type of population:
not specified
Ethical approval:
not specified
Route of administration:
dermal

Results and discussion

Results of examinations:
Patch testing in man with the dry material produced reactions in sensitised individuals but when formulated into rubber and re-tested no reactions were observed.

Applicant's summary and conclusion

Conclusions:
Patch testing in man with the dry material produced reactions in sensitised individuals but no reactions were observed when formulated into rubber.